Journal: Pharmaceutical Analytical Chemistry PDF
Published: 27-Sep-15 Volume: 1 Issue: 1
DOI: 10.4172/2471-2698.1000102 ISSN: 2471-2698
Authors: Mahendra Kumar Trivedi, Alice Branton , Dahryn Trivedi, Gopal Nayak , Khemraj Bairwa and Snehasis Jana
Citation: Trivedi MK, Branton A, Trivedi D, Nayak G, Bairwa K, et al (2015) Physicochemical and Spectroscopic Characterization of Biofield Energy Treated p-Anisidine. Pharm Anal Chem Open Access 1: 102. doi:10.4172/2471- 2698.1000102
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The p-anisidine is widely used as chemical intermediate in the production of various dyes, pigments, and pharmaceuticals. This study was aimed to evaluate the effect of biofield energy treatment on the physicochemical and spectroscopic properties of p-anisidine. The study was performed after dividing the sample in two groups; one was remained as untreated and another was subjected to Mr. Trivedis biofield energy treatment. Afterward, both the control and treated samples of p-anisidine were evaluated using X-ray diffraction (XRD), surface area analyzer, differential scanning calorimetry (DSC), thermogravimetric analysis-derivative thermogravimetry (TGA-DTG), Fourier transform infrared (FT-IR), and ultraviolet-visible (UV-Vis) spectroscopy. The XRD analysis showed the increase in unit cell volume from 683.81 ? 690.18 × 10-24 cm3 and crystallite size from 83.84?84.62 nm in the treated sample with respect to the control. The surface area analysis exhibited the significant increase (25.44%) in the surface area of treated sample as compared to control. The DSC thermogram of control p-anisidine showed the latent heat of fusion and melting temperature and 146.78 J/g and 59.41°C, respectively, which were slightly increased to 148.89 J/g and 59.49°C, respectively after biofield treatment. The TGA analysis showed the onset temperature of thermal degradation at 134.68°C in the control sample that was increased to 150.02°C after biofield treatment. The result showed about 11.39% increase in onset temperature of thermal degradation of treated p-anisidine as compared to the control. Moreover, the Tmax (temperature at which maximum thermal degradation occurs) was also increased slightly from 165.99°C (control) to 168.10°C (treated). This indicated the high thermal stability of treated p-anisidine as compared to the control. However, the FT-IR and UV spectroscopic studies did not show any significant changes in the spectral properties of treated p-anisidine with respect to the control.
All together, the XRD, surface area and thermal analysis suggest that Mr. Trivedis biofield energy treatment has the impact on physical and thermal properties of the treated p-anisidine.
In brief, the XRD diffractogram of biofield treated p-anisidine showed the slight increase in unit cell volume, crystallite size and molecular weight as compared to the control. The intensity of XRD peaks was also increased in treated sample as compared to the control. The surface area analysis showed a significant increase (25.44%) in the surface area of biofield treated p-anisidine with respect to the control. The DSC analysis showed the slight increase in latent heat of fusion from 146.78 J/g (control) to 148.89 J/g in the treated sample. The TGA/DTG analysis showed the increase in onset and end set temperature of thermal degradation by 11.39% and 3.86%, respectively in treated sample with respect to the control. Moreover, the Tmax was also increased slightly from 165.99 (control) to 168.10°C in treated sample of p-anisidine.
Overall, it can be concluded that Mr. Trivedis biofield energy treatment has the impact on physical and thermal properties of p-anisidine with respect to the control. Based on this, it is assumed that biofield treated p-anisidine could be more useful as a chemical intermediate in the organic synthesis of various dyes and pharmaceuticals.