Journal: Molecular Pharmaceutics & Organic Process Research PDF
Published: 19-Oct-15 Volume: 3 Issue: 3 Pages: 001-005
DOI: 10.4172/2329-9053.1000129 ISSN: 2329-9053
Authors: Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Khemraj Bairwa and Snehasis Jana
Citation: Trivedi MK, Branton A, Trivedi D, Nayak G, Bairwa K, et al. (2015) Evaluation of Physical, Thermal and Spectral Parameters of Biofield Energy Treated Methylsulfonylmethane. J Mol Pharm Org Process Res 3: 129. doi:10.4172/2329-9053.1000129
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The methylsulfonylmethane (MSM) is an organosulfur compound having sulfonyl functional group. It is occurred naturally in some primitive plants and used in disease related to chronic pain, inflammation, and arthritis. This study was attempted to evaluate the impact of biofield energy treatment on the physical, thermal, and spectral properties of MSM. The study was performed in two groups viz. the control group was remained as untreated, while the treated group was subjected to Mr. Trivedis biofield energy treatment. After that, both the control and treated samples were analyzed using surface area analyzer, X-ray diffraction (XRD), thermogravimetric analysisderivative thermogravimetry (TGA-DTG), differential scanning calorimetry (DSC), and Fourier transform infrared (FTIR) spectroscopy. The surface area analysis exhibited a significant decrease in the surface area of treated sample by 22.96% as compared to the control. The XRD analysis showed the significant increase in average crystallite size by 49.20% in the treated sample with respect to the control. The DSC analysis showed the significant increase (67.20%) in latent heat of fusion of treated sample with respect to the control. The TGA analysis showed the onset temperature of thermal degradation at 170°C in the control sample that was slightly decreased to 168.05°C after biofield treatment. Moreover, the Tmax (maximum thermal degradation temperature) was also decreased slightly from 186.66°C (control) to 183.38°C (treated). This indicated the early phase of vaporization in treated sample as compared to the control. The FT-IR spectroscopic study exhibited the alteration in wavenumber of S=O group that suggests the effect of biofield treatment on force constant and bond strength of MSM molecules.
Altogether, the surface area, XRD, thermal analysis and FT-IR spectroscopy suggests that Mr. Trivedis biofield energy treatment has the impact on physical, thermal, and spectral properties of MSM.
In summary, the result of present study showed the decrease in surface area of treated sample with respect to the control. This might be due to increase in crystallite size of treated sample as evidenced by XRD analysis. The TGA-DTG study showed the slight decrease in onset and end-set temperature of thermal degradation. The DSC analysis exhibited the significant increase in latent heat of fusion of treated sample as compared to the control. This may be due to the increased intermolecular bonding of MSM molecule. The effect of biofield energy treatment on MSM molecule showed time dependent shifting of S=O stretching frequencies in FT-IR spectra with respect to the control. This might be due to the decrease in force constant and atomic bond strength of MSM molecule.
Overall, the present study concluded the significant impact of Mr. Trivedis biofield energy treatment on physical, thermal and spectroscopic properties of MSM with respect to the control. Based on this, it is expected that by altering the physicochemical properties using Mr. Trivedis biofield energy treatment, the MSM can be changed into the more effective form with respect to its pharmacological activity as well as solvent in organic synthesis.