Journal: Science Journal of Analytical Chemistry PDF
Published: 21-Dec-15 Volume: 3 Issue: 6 Pages: 127-134
DOI: 10.11648/j.sjac.20150306.18 ISSN: 2376-8045 (Print) 2376-8053 (Online)
Authors: Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Rakesh Kumar Mishra, Snehasis Jana
Citation: Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Rakesh Kumar Mishra, Snehasis Jana. Characterization of Physical, Thermal and Spectral Properties of Biofield Treated 2-Aminopyridine. Science Journal of Analytical Chemistry. Vol. 3, No. 6, 2015, pp. 127-134. doi: 10.11648/j.sjac.20150306.18
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2-Aminopyridine is an important compound, which is used as intermediate for the synthesis of pharmaceutical compounds. The present work was aimed to assess the effect of Mr. Trivedis biofield energy treatment on the physical, thermal and spectral characteristics of 2-AP. The work was accomplished by dividing the sample in two parts i.e. one part was remained untreated, and another part had received biofield energy treatment. Subsequently, the samples were analyzed using various characterization techniques such as X-ray diffraction, differential scanning calorimetry, thermogravimetric analysis, ultra violet-visible spectroscopy, and Fourier transform infrared spectroscopy. The XRD analysis revealed a decrease in crystallite size of the treated sample (91.80 nm) as compared to the control sample (97.99 nm). Additionally, the result showed an increase in Braggs angle (2?) of the treated sample as compared to the control. The DSC and Differential thermal analysis analysis showed an increase in melting temperature of the treated 2-AP with respect to the control. Moreover, the latent heat of fusion of the treated sample was increased by 3.08%. The TGA analysis showed an increase in onset of thermal degradation (Tonset), and maximum thermal decomposition temperature (Tmax) of the treated 2-AP as compared to the control sample. Additionally, the treated sample showed a reduction in weight loss as compared with the control indicating higher thermal stability of the sample. UV-visible analysis showed no changes in the absorption peak of the treated sample as compared to the control. The FT-IR spectroscopic results showed downward shifting of C-H stretching vibration 2991?2955 cm-1 in treated sample with respect to the control.
In summary, the results demonstrated that the biofield energy treatment has influenced the physical, thermal and spectral properties of 2-AP. The XRD study showed a decrease in crystallite size as well as an increase in Braggs angle (2?) of the XRD peaks as compared to the control sample. It is speculated that biofield energy treatment may cause tensile stress in the treated 2-AP molecules that led to a shift in 2? angle and decrease in crystallite size. The DSC and DTA exhibited the increase in melting temperature of the treated sample. However, the latent heat of fusion of the treated 2-AP was decreased as compared to the control. The biofield energy might have altered the stored internal energy in the treated sample that led to a reduction in latent heat of fusion. The TGA analysis showed an increase in onset of thermal degradation, Tmax, and reduction in weight loss of the treated 2-AP, which corroborated the high thermal stability of sample as compared to the control. The FT-IR results showed downward shifting in vibration bands of C-H group stretching as compared to the control. Overall, the result demonstrated that smaller crystallite size and good thermal stability (more temperature stable with higher reaction rate) might improve its applicability as better intermediate for the synthesis of pharmaceutical compounds.